Current partner codePEPTIDESDE
NCT03289741·Phase 4·INTERVENTIONAL

A Study to Evaluate Patient Experience in the Therapy of Neuroendocrine Tumors Treated With Octreotide Long Acting Release Versus Lanreotide

Status

Completed

Phase

Phase 4

Enrollment

51

Locations

7

Results

Posted

Publications

1

Study summary

What the protocol is testing.

This study is being done to evaluate differences in patient experience during treatment with octreotide LAR and lanreotide.

Interventions

Treatment arms and agents.

DRUG

Octreotide

Patients will receive three monthly injections every 28 (+/- 3) days. Octreotide LAR for 3 injections followed by lanreotide for 3 injections

DRUG

LAR Lanreotide

Patients will receive three monthly injections every 28 (+/- 3) days. Lanreotide for 3 injections followed by octreotide LAR for 3 injections

BEHAVIORAL

Questionnaires

Baseline questionnaire, Post-treatment questionnaire (after the first 3 injections), Preference questionnaire and Pain Score Diary.

Timeline

From registration to results.

  1. First posted

    Sep 21, 2017

  2. Study start

    Sep 19, 2017

  3. Primary completion

    Apr 10, 2023

  4. Study completion

    Apr 10, 2023

  5. Results posted

    May 9, 2025

  6. Registry updated

    May 9, 2025

Outcomes

What the study measures.

Primary outcomes

Mean Pain Scores at 3 Months

Time frame · 3 months

Patients will rate, on a numeric scale of 0 to 10, with 0 being No pain" to 10 being "Worst pain ever" the pain or discomfort experienced with the SSA injection.

Secondary outcomes

Not reported in the indexed record.

Eligibility

Who can take part.

Minimum age
18 Years
Maximum age
Not reported
Sex
ALL
Healthy volunteers
No

Inclusion Criteria: * Willing and able to provide written informed consent for the trial * ≥ 18 years of age * Histologically- or cytologically- confirmed locally advanced or metastatic WDNET * SSA therapy is recommended by physician for disease management, and has not yet begun * ECOG performance status of 0, 1, or 2 Exclusion Criteria: * Currently participating in a study of an investigational agent * Prior chemotherapy, targeted small molecule therapy within 2 weeks prior to study Day 1 or not recovered (i.e., ≤ Grade 1 or at baseline) from adverse events due to a previously administered agent \*Note: Subjects with ≤ Grade 2 neuropathy or ≤ Grade 2 alopecia are an exception to this criterion and may qualify for the study * No concurrent chemotherapy or targeted small molecule therapy * If received major surgery, not recovered adequately from the toxicity and/or complications from the intervention prior to starting the study * Known additional malignancy that is progressing or requires active treatment * Active infection requiring systemic therapy * Known psychiatric or substance abuse disorders that would interfere with cooperation with the requirements of the trial

Study locations

7 registered sites.

United States. Showing up to 24 locations stored in the fast local snapshot.

Memorial Sloan Kettering Basking Ridge

Basking Ridge, New Jersey, United States

Memorial Sloan Kettering Monmouth

Middletown, New Jersey, United States

Memorial Sloan Kettering Bergen

Montvale, New Jersey, United States

Memorial Sloan Kettering Commack

Commack, New York, United States

Memorial Sloan Kettering West Harrison

Harrison, New York, United States

Memorial Sloan Kettering Cancer Center

New York, New York, United States

Memorial Sloan Kettering Nassau

Uniondale, New York, United States

Related trials

More studies on Octreotide.

Related PeptideStat pages

Put the record in context.

Research pages describe evidence. Vendor pages, where available, describe independently tracked research-product listings and are not clinical recommendations.