Inclusion Criteria:
* Patients who are undergoing temporary ileostomy (loop or end ileostomy) regardless of the indication or technique used (open or laparoscopy) as part of their regular standard of care
* Age- 18-80 years old
* Normal routine laboratories (CMP, CBC, CRP, amylase, lipase)
* Permitted medications will include biologicals which dose has not been changed for \> 6 months, and immunosuppressant therapy which dose has not been changed for 3 months (i.e. codeine sulfate, loperamide, or Lomotil)
Exclusion Criteria:
* Emergency need for ileostomy
* Pregnant or nursing
* Malnutrition or requiring parenteral or enteral nutrition
* Known intestinal obstruction, stricture, or adhesions that would predispose the patient to the development of intestinal obstruction, perforation, hemorrhage, or intestinal abscess
* Intestinal fistulas or abscess proximal to the ostomy
* Small bowel resection greater than 50 cm.
* Clinically significant cardiovascular, renal, pulmonary, endocrine, immunologic, dermatology, neurological or psychiatric disorders
* Cholelithiasis or pancreatitis
* Family history of colorectal cancer or familial polyposis
* Cancer in the last 5 years
* History of HIV, Hepatitis B or C, or other acute systemic or intestinal infections requiring antibiotics
* Use of GLP1 analogues which may increase the risk of acute pancreatitis
* Treatment of Octreotide