BIOLOGICAL
Biological sampling
Blood sample (5mL) for metabolomic dosage and Fecal sample for ARN16s sequencing
Microbiotic Analysis in Digestive Endocrine Tumors
Status
Unknown
Phase
Not applicable
Enrollment
50
Locations
0
Results
Not posted
Publications
0
Study summary
What the protocol is testing.
Incidence of digestive neuroendocrine tumors are increasing. Analysis of individual microbiota is a way to explore new neoplastic mechanisms, tumor identification and therapeutic orientations. This prospective pilot study aims to describe fecal bacterial phylogeny of patients with digestive neuroendocrine tumor. Bacterial genomic signature will be recorded at initiation of Lanreotide treatment in naive patient with digestive neuroendocrine tumor (pancreas or small intestine), metastatic or locally advanced, as well as after one year follow up.
Interventions
Treatment arms and agents.
Timeline
From registration to results.
First posted
Dec 13, 2019
Study start
Jan 2020
Primary completion
Jan 2022
Study completion
Jan 2023
Results posted
Not reported
Registry updated
Dec 13, 2019
Outcomes
What the study measures.
Primary outcomes
bacterial genomic signature
Time frame · Baseline visit
bacterial genomic signature by fecal ARN16S analysis at enrollment
Secondary outcomes
Not reported in the indexed record.
Eligibility
Who can take part.
- Minimum age
- 18 Years
- Maximum age
- Not reported
- Sex
- ALL
- Healthy volunteers
- No
Inclusion Criteria: * 18 years old or older * naive patient with digestive neuroendocrine tumor (pancreas (cytology or histology per endoscopy or on surgical specimen) or small intestine), secreting or not, initiating a extended release Lanreotide treatment * registered with a social security scheme Exclusion Criteria: * medical contraindication to somatostatine analogs use * history of extended release somatostatine analogs treatment * antibiotic use or colonoscopic purge in the last 3 weeks preceding fecal sample * pregnant or breastfeeding women * person requiring tutorship, guardianship, or person legally protected
Study locations
0 registered sites.
No country data reported. Showing up to 24 locations stored in the fast local snapshot.
No study locations reported.
Publications
Results and literature.
No PMID-linked publications were present in this registry snapshot.
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Related PeptideStat pages
Put the record in context.
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