Acupuncture in the Freeze-all IVF Cycle

The study will be conducted on patients with DOR attending our reproductive medicine center for proposed IVF-ET between June 2021and December 2022. The trial is designed as a randomized, controlled clinical trial with two groups established by 1:1 equal allocation, a treatment group with interventions using acupuncture to tonify the kidneys and regulate blood and a control group treated using conventional Western medicine. Random numbers will be prepared by an independent third-party statistician who prepared a list of random group codes for this study. Enrolled subjects will be given a subject number during the screening process and, upon formal enrolment, will be randomly assigned to either the test or control group with a corresponding random number. The acupoints used will be: Zhongwan (RN12) ：The needle should be punctured for 1-1.2 inches and retained for 30 minutes. Qihai(RN6): The needle should be punctured for 1-1.2 inches and retained for 30 minutes. Guanyuan(RN4): The needle should be punctured for 0.8-1.2 inches and retained for 30 minutes. Zhongji(RN3): The needle should be punctured for 0.8-1.0 inches and retained for 30 minutes. Guilai(ST29): The needle should be punctured for 0.8-1.0 inches and retained for 30 minutes. Shenshu(BL23): The needle should be punctured for 0.8-1.0 inches and retained for 30 minutes. Ciliao(BL28): The needle should be punctured for 1-1.2 inches and retained for 30 minutes. Xuehai(SP10): The needle should be punctured for 1-1.5 inches and retained for 30 minutes. Zusanli(ST36): The needle should be punctured for 1-1.5 inches and retained for 30 minutes. Diji(SP8): The needle should be punctured for 1-1.2 inches and retained for 30 minutes. Sanyinjiao(SP6): The needle should be punctured for 1-1.2 inches and retained for 30 minutes. Taixi(KI6): The needle should be punctured for 0.8-1.2 inches and retained for 30 minutes. Baihui(DU20): The needle should be punctured for 0.5-1.0 inches and retained for 30 minutes. Yintang(EX-HN3): The needle should be punctured for 0.5-1.0 inches and retained for 30 minutes. The Acupuncture intervention will start on the 5th day of the menstruation cycle, which will be carried out 1 time per day,at least 5 times a week, lasts for 10-15days. All operations were performed by experienced acupuncturists. After ET, both the control group and the treatment group will be treated with conventionally with no TCM intervention. Serum human chorionic gonadotropin (hCG) will be measured, and an hCG\>30 IU will be considered to indicate biochemical pregnancy. Ultrasound monitoring will be performed 30 days after ET to calculate the clinical pregnancy rate.