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NCT05794581·Phase 1·INTERVENTIONAL

A Study to Assess the Effects of CT-868 Treatment on Glucose Homeostasis in Participants with Type 1 Diabetes

Status

Completed

Phase

Phase 1

Enrollment

32

Locations

1

Results

Not posted

Publications

0

Study summary

What the protocol is testing.

This study will be conducted primarily to evaluate the effects of CT-868 on glucose homeostasis in participants with Type 1 Diabetes Mellitus.

Interventions

Treatment arms and agents.

DRUG

CT-868

CT-868

DRUG

Placebo

Placebo as SC Injection

DRUG

Victoza

Victoza as active comparator as SC Injection

Timeline

From registration to results.

  1. First posted

    Apr 3, 2023

  2. Study start

    Mar 21, 2023

  3. Primary completion

    Mar 6, 2024

  4. Study completion

    Apr 6, 2024

  5. Results posted

    Not reported

  6. Registry updated

    Dec 27, 2024

Outcomes

What the study measures.

Primary outcomes

To assess area under the curve (AUC) in glucose metabolism during MMTT

Time frame · Baseline up to 4 days

Secondary outcomes

To assess changes in continuous glucose monitoring (CGM) measures

Time frame · Baseline up to 4 days

Area under the acetaminophen concentration-time (AUC)

Time frame · 0 - 300 minutes

Eligibility

Who can take part.

Minimum age
18 Years
Maximum age
65 Years
Sex
ALL
Healthy volunteers
Yes

Inclusion Criteria: * Female or male adults with Type 1 diabetes * Ages 18-65 years * Type 1 DM for at least 3 years * Using an insulin pump or multiple daily injections (MDI) for at least 3 months * BMI 25.0 - 35.0 Exclusion Criteria: * Significant medical history * Uncontrolled diabetes * History of surgical treatment for weight loss * History of malignancy

Study locations

1 registered sites.

United States. Showing up to 24 locations stored in the fast local snapshot.

Carmot Clinical Research Unit 101

Chula Vista, California, United States

Publications

Results and literature.

No PMID-linked publications were present in this registry snapshot.

Primary links

Continue at the source.

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Related PeptideStat pages

Put the record in context.

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