To Evaluate the Efficacy and Safety of SAL056 for Postmenopausal Women With Osteoporosis at High Fracture Risk

Inclusion Criteria: 1. Postmenopausal women with the ability to live independently (≥45 and ≤80 years); 2. The patient has a body mass index(BMI) of 18.0 kg/m2 to 30 kg/m2； The patient has one of the following diagnostic criteria for osteoporosis and subject has at least 2 consecutive vertebrae region (L1 to L4) that are evaluable by dual-energy x-ray absorptiometry (DXA)，a) History of hip/vertebra fragility fracture and bone mineral density (BMD) T-score ≤-1; b）the axial bone (lumbar , femoral neck or total hip) mineral density (BMD) T-score ≤-2.50;c) Bone mineral density (BMD) T-score ≥-2.5 and ≤-1 with proximal humerus, pelvis, or distal forearm end fragility fracture Exclusion Criteria: 1. In addition to postmenopausal osteoporosis, the other diseases affecting bone metabolism; 2. Patients with other diseases affecting calcium or bone metabolism; 3. Received anti-osteoporosis treatment that does not meet protocol requirements; 4. Received medication that affects bone metabolism prior to screening, or is planned to use prohibited drugs/non-drug therapy under the protocol during the study period; 5. Patients requiring long-term or continuous use of digoxin and other digitalis drugs during the trial; 6. Patients with other severe underlying diseases； Patients with abnormal indicators that does not meet protocol requirements during the screening periodlaboratory tests