Change From Baseline in Fasting Plasma Glucose at Week 12
Time frame · Baseline and Week 12
Fasting plasma glucose will be measured in mmol/L at baseline and at week 12. Change will be calculated as the week 12 value minus the baseline value. A negative change indicates a reduction in fasting plasma glucose.
Proportion of Participants Achieving HbA1c Below 6.5% at Week 12
Time frame · Week 12
The proportion of participants with glycated hemoglobin (HbA1c) below 6.5% at week 12 will be calculated as the number of participants meeting this threshold divided by the number of participants assessed.
Change From Baseline in Body Weight at Week 12
Time frame · Baseline and Week 12
Body weight will be measured in kilograms at baseline and at week 12. Change will be calculated as the week 12 value minus the baseline value. A negative change indicates weight loss.
Percentage Change From Baseline in Body Weight at Week 12
Time frame · Baseline and Week 12
Percentage change in body weight will be calculated as the difference between body weight at week 12 and baseline body weight, divided by baseline body weight and multiplied by 100. A negative value indicates weight loss.
Proportion of Participants Achieving at Least 5% Weight Loss at Week 12
Time frame · Baseline and Week 12
The proportion of participants whose body weight decreases by at least 5% from baseline to week 12 will be calculated.
Change From Baseline in Body Mass Index at Week 12
Time frame · Baseline and Week 12
Body mass index will be calculated in kg/m² at baseline and at week 12. Change will be calculated as the week 12 value minus the baseline value. A negative change indicates a reduction in body mass index.
Change From Baseline in Waist Circumference at Week 12
Time frame · Baseline and Week 12
Waist circumference will be measured in centimeters at baseline and at week 12. Change will be calculated as the week 12 value minus the baseline value. A negative change indicates a reduction in waist circumference.
Change From Baseline in LDL Cholesterol at Week 12
Time frame · Baseline and Week 12
Low-density lipoprotein cholesterol will be measured in mmol/L at baseline and at week 12. Change will be calculated as the week 12 value minus the baseline value.
Change From Baseline in HDL Cholesterol at Week 12
Time frame · Baseline and Week 12
High-density lipoprotein cholesterol will be measured in mmol/L at baseline and at week 12. Change will be calculated as the week 12 value minus the baseline value.
Change From Baseline in Total Cholesterol at Week 12
Time frame · Baseline and Week 12
Total cholesterol will be measured in mmol/L at baseline and at week 12. Change will be calculated as the week 12 value minus the baseline value.