Current partner codePEPTIDESDE
InvestigationalWeight lossSubcutaneousEvidence 4/5

Cagrilintide

Also known as: AM833

Long-acting amylin analog that slows gastric emptying and reinforces satiety; studied in combination with semaglutide (CagriSema).

Illustrative subcutaneous database profile for Cagrilintide
Illustrative profileSubcutaneous
Database profileInvestigational
CagrilintideWeight loss
Drug class
Amylin analog
Primary targets
Amylin / CTR
Dose reference
Trial doses up to 4.5 mg weekly
Half-life
~7 days
Developer / origin
Novo Nordisk
Reference year
2021
Evidence score
4/5 - Phase 2 human evidence
Evidence 4/5

Phase 2 human evidence

Cagrilintide has randomized phase 2 human weight-management data and combination evidence with semaglutide, but it remains investigational.

Investigational compound with human randomized or phase 2/3 evidence.

Evidence basis

  • Human phase 2 obesity trial
  • CagriSema clinical development
  • No approved indication yet

How to read this entry

Dose references and half-life values are pulled from trial protocols, labels, reviews, or published summaries where available. They are context for research and comparison, not a personal dosing recommendation.

Status matters: approved drugs have regulated indications; investigational compounds are still being studied; research-only peptides do not have established human dosing, safety, or efficacy for consumer use.

Cagrilintide guides

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Activates GLP-1 and GIP receptors to improve glycemic control and reduce appetite + body weight.

Semaglutide

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5/5
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Mimics the incretin GLP-1, slowing gastric emptying and reducing appetite while improving insulin secretion.

Liraglutide

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Weight lossApproved

Daily GLP-1 analog. Reduces appetite and improves glycemic control via the same incretin pathway as semaglutide.

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