DRUG
DDAVP
Patients Receiving DDAVP prior to operation
DDAVP in the Reduction of Post-operative Ecchymosis in Rhinoplasty
Status
Terminated
Phase
Phase 2
Enrollment
14
Locations
1
Results
Posted
Publications
0
Study summary
What the protocol is testing.
This is study looking at the use of a medication, Desmopressin acetate (DDAVP), to reduce bleeding, swelling, and bruising in patients undergoing cosmetic nose surgery. DDAVP is a drug used in patients with bleeding disorders. It works by activating molecules in the blood stream called platelets that promote clotting. In the study, participants who are have cosmetic nose surgery (rhinoplasty) will be randomly assigned to receive or not receive medication. Photographs taken before and shortly after surgery will be evaluated for the amount of bruising and swelling. Patients with heart, lung, kidney, or liver problems are not eligible to participate.
Interventions
Treatment arms and agents.
Timeline
From registration to results.
First posted
Nov 13, 2013
Study start
Dec 2013
Primary completion
Jun 25, 2015
Study completion
Jun 25, 2015
Results posted
Aug 16, 2023
Registry updated
Aug 16, 2023
Outcomes
What the study measures.
Primary outcomes
Reduction in Ecchymosis and Swelling
Time frame · surgery to 8 days post-operatively
Photographs taken preoperatively at 1 day and 8 days post-operatively will be analyzed for bruising
Secondary outcomes
Patient Behavior Factors
Time frame · Surgery to 3 weeks post-operatively
Looking at the time it takes for patients to feel comfortable wearing makeup, going out in public, and returning to work
Eligibility
Who can take part.
- Minimum age
- 18 Years
- Maximum age
- 80 Years
- Sex
- ALL
- Healthy volunteers
- No
Inclusion Criteria: * Undergoing Rhinoplasty where nasal bone osteotomy is necessary Exclusion Criteria: * Heart Disease * Renal Disease with decreased GFR * Liver Disease
Study locations
1 registered sites.
United States. Showing up to 24 locations stored in the fast local snapshot.
Lyndhurst Surgery Center
Lyndhurst, Ohio, United States
Publications
Results and literature.
No PMID-linked publications were present in this registry snapshot.
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Related PeptideStat pages
Put the record in context.
Research pages describe evidence. Vendor pages, where available, describe independently tracked research-product listings and are not clinical recommendations.