DRUG
carbetocin 100 mcg
a 10 cm syringe containing 100 mcg carbetocin just before skin incision of myomectomy.
the Effect of Carbetocin in Decreasing Intraoperative Blood Loss in Abdominal Myomectomy
Status
Completed
Phase
Phase 4
Enrollment
138
Locations
1
Results
Not posted
Publications
1
Study summary
What the protocol is testing.
To investigate the effectiveness of carbetocin on reducing intraoperative blood loss during abdominal myomectomy
Interventions
Treatment arms and agents.
DRUG
placebo
a 10 cm syringe normal saline IV given just before skin incision of myomectomy.
Timeline
From registration to results.
First posted
Sep 10, 2019
Study start
Sep 10, 2019
Primary completion
Feb 10, 2020
Study completion
Feb 20, 2020
Results posted
Not reported
Registry updated
Apr 8, 2020
Outcomes
What the study measures.
Primary outcomes
Mean amount of intraoperative blood loss
Time frame · intraoperative
Mean amount of intraoperative blood loss in ml
Secondary outcomes
Not reported in the indexed record.
Eligibility
Who can take part.
- Minimum age
- 25 Years
- Maximum age
- 50 Years
- Sex
- FEMALE
- Healthy volunteers
- No
Inclusion Criteria: * • Patients presenting for abdominal myomectomy with documented uterine fibroids on pelvic imaging * Age ≥ 25 years and ≤ 50 years * Pre-operative hemoglobin \>10 g/dl * Ability to understand and the willingness to sign a written informed consent. * Admissible medical/surgical history * Five or less symptomatic uterine myomas * symptomatic stage 3 to 6 fibroids, according to FIGO staging Exclusion Criteria: * • Post-menopausal women * Patients with known bleeding/clotting disorders * Patients with a history of gynecologic malignancy * Hypertension. * Cardiac and Pulmonary diseases. * History of allergic reactions attributed to carbetocin
Study locations
1 registered sites.
Egypt. Showing up to 24 locations stored in the fast local snapshot.
Giza hospital
Giza, Egypt
Related trials
More studies on Carbetocin.
NCT IDStudyPhase / statusEnrollmentUpdated
The Efficacy of Carbitocin in Reduction of Blood Loss During Myomectomy
Alex Ekwueme Federal University Teaching Hospital · Blood Loss, Surgical
Early Phase 1
Not yet recruiting
900
2026-07
Carbetocin Monotherapy Versus Carbetocin Plus Oxytocin Infusion in Elective Cesarean Delivery: A Non-Inferiority Trial
Mansoura University · Postpartum Hemorrhage · Uterine Atony
Phase 4
Not yet recruiting
332
2026-06
Carbetocin Uterotonic Treatment in Twin Pregnancies for Prevention of Postpartum Hemorrhage
Sheba Medical Center · Postpartum Hemorrhage · Twin Pregnancy
Phase 4
Recruiting
120
2026-05
Comparing the Dose-response Profiles of Uterotonics After Initial Carbetocin Administration - an Ex-vivo Study in Desensitized Human Myometrium
Samuel Lunenfeld Research Institute, Mount Sinai Hospital · Postpartum Hemorrhage
Not applicable
Recruiting
32
2026-04
Comparative Efficacy of Carbetocin and Oxytocin in Parturients at Risk of Atonic Postpartum Hemorrhage Undergoing Elective Cesarean Delivery
Samuel Lunenfeld Research Institute, Mount Sinai Hospital · Post Partum Hemorrhage
Not applicable
Recruiting
160
2026-04
Effect of Co-administration of Carbetocin and Calcium Chloride on Uterine Tone in Patients Undergoing Elective Cesarean Delivery
Samuel Lunenfeld Research Institute, Mount Sinai Hospital · Postpartum Hemorrhage (Primary)
Not applicable
Recruiting
120
2026-04
Comparison of the Effect of Carbetocin Versus Oxytocin in the Prevention of Postpartum Hemorrhage After Emergency Caesarean Section in Antenatal Low-risk Patients
Ankara Etlik City Hospital · Postpartum Hemorrhage \(PPH\)
Not applicable
Completed
300
2026-02
Carbetocin Myocardium Trial 2014 Part 2
Oslo University Hospital · Pregnancy Complications
Phase 4
Completed
240
2026-02
Related PeptideStat pages
Put the record in context.
Research pages describe evidence. Vendor pages, where available, describe independently tracked research-product listings and are not clinical recommendations.