HygiRelief Procedure and HygiSample Evaluation for Functional Constipation

Inclusion Criteria: 1. Patient's age is between 18 and 80 years old 2. Patient diagnosed with Rome IV Functional Constipation (Attachment C2) 3. Patient is currently managed with Linzess and willing to stop taking it for study duration Exclusion Criteria: 1. Patient has functional bowel disorders characterized by alternating bowel habits (diarrhea/constipation) 2. Patient has any other condition that, in the opinion of the investigator, may adversely affect the compliance or safety of the patient or would limit the patient's ability to complete the study 3. Patient has any of the contraindications listed below: 1. Cardiac: Congestive heart failure (NYHA class III or IV or EF \<50%) 2. GI: Intestinal perforation, carcinoma of the rectum, fissures or fistula, severe hemorrhoids, abdominal hernia, recent colon, rectal, or abdominal surgery 3. GU: Renal insufficiency (CC \< 60 ml/min/173m2), cirrhosis with ascites 4. Abdominal surgery within the last 6 months 5. Pregnancy 4. Patient took antibiotics within two months of starting the study