DRUG
Carbetocin
100 mcg of Carbetocin intravenous injection
Uterotonics for Severe Preeclampsia
Status
Completed
Phase
Not applicable
Enrollment
124
Locations
1
Results
Not posted
Publications
0
Study summary
What the protocol is testing.
The study compares the effect of Intravenous carbetocin versus combined use of intravenous oxytocin and rectal misoprostol for prevention of postpartum hemorrhage during delivery of women with severe preeclampsia
Interventions
Treatment arms and agents.
DRUG
Oxytocin
10 IU oxytocin IV drip
DRUG
Misoprostol
400 mcg rectal
Timeline
From registration to results.
First posted
Feb 16, 2021
Study start
Jan 1, 2020
Primary completion
Dec 31, 2020
Study completion
Feb 10, 2021
Results posted
Not reported
Registry updated
Feb 16, 2021
Outcomes
What the study measures.
Primary outcomes
The rate of postpartum hemorrhage more than 1000 ml
Time frame · 30 minutes
the amount of bleeding during and after CS
Secondary outcomes
Not reported in the indexed record.
Eligibility
Who can take part.
- Minimum age
- Not reported
- Maximum age
- Not reported
- Sex
- FEMALE
- Healthy volunteers
- No
Inclusion Criteria: * Pregnant women which diagnosed with severe pre-eclampsia. * Singleton pregnancy. * Termination of pregnancy by Cesarean section after 28 weeks of gestation. Exclusion Criteria: * Suspected or proven placental abruption. * Known placenta Previa or acreata. * Multiple pregnancies. * Obesity (BMI \>35). * Anemia (\<9 g/dl). * Retained placental tissues. * Big baby (\> 4 kg). * Presence of coagulopathy. * Polyhydramnios. * Presence of Uterine fibroids. * Medical diseases as; cardiac, liver, renal or endocrine diseases. * General anesthesia.
Study locations
1 registered sites.
Egypt. Showing up to 24 locations stored in the fast local snapshot.
Assiut Faculty of Medicine
Asyut, Egypt
Publications
Results and literature.
No PMID-linked publications were present in this registry snapshot.
Related trials
More studies on Carbetocin.
NCT IDStudyPhase / statusEnrollmentUpdated
The Efficacy of Carbitocin in Reduction of Blood Loss During Myomectomy
Alex Ekwueme Federal University Teaching Hospital · Blood Loss, Surgical
Early Phase 1
Not yet recruiting
900
2026-07
Carbetocin Monotherapy Versus Carbetocin Plus Oxytocin Infusion in Elective Cesarean Delivery: A Non-Inferiority Trial
Mansoura University · Postpartum Hemorrhage · Uterine Atony
Phase 4
Not yet recruiting
332
2026-06
Carbetocin Uterotonic Treatment in Twin Pregnancies for Prevention of Postpartum Hemorrhage
Sheba Medical Center · Postpartum Hemorrhage · Twin Pregnancy
Phase 4
Recruiting
120
2026-05
Comparing the Dose-response Profiles of Uterotonics After Initial Carbetocin Administration - an Ex-vivo Study in Desensitized Human Myometrium
Samuel Lunenfeld Research Institute, Mount Sinai Hospital · Postpartum Hemorrhage
Not applicable
Recruiting
32
2026-04
Comparative Efficacy of Carbetocin and Oxytocin in Parturients at Risk of Atonic Postpartum Hemorrhage Undergoing Elective Cesarean Delivery
Samuel Lunenfeld Research Institute, Mount Sinai Hospital · Post Partum Hemorrhage
Not applicable
Recruiting
160
2026-04
Effect of Co-administration of Carbetocin and Calcium Chloride on Uterine Tone in Patients Undergoing Elective Cesarean Delivery
Samuel Lunenfeld Research Institute, Mount Sinai Hospital · Postpartum Hemorrhage (Primary)
Not applicable
Recruiting
120
2026-04
Comparison of the Effect of Carbetocin Versus Oxytocin in the Prevention of Postpartum Hemorrhage After Emergency Caesarean Section in Antenatal Low-risk Patients
Ankara Etlik City Hospital · Postpartum Hemorrhage \(PPH\)
Not applicable
Completed
300
2026-02
Carbetocin Myocardium Trial 2014 Part 2
Oslo University Hospital · Pregnancy Complications
Phase 4
Completed
240
2026-02
Related PeptideStat pages
Put the record in context.
Research pages describe evidence. Vendor pages, where available, describe independently tracked research-product listings and are not clinical recommendations.