Current partner codePEPTIDESDE
NCT07701083·Phase 1·INTERVENTIONAL

A Study of Eloralintide (LY3841136) in Healthy Participants

Status

Not yet recruiting

Phase

Phase 1

Enrollment

58

Locations

2

Results

Not posted

Publications

0

Study summary

What the protocol is testing.

The main purpose of this study is to learn about safety, tolerability and how well the body processes two different eloralintide solutions. Participation in this study will last about 13 weeks, including screening, inpatient treatment, and follow-up.

Interventions

Treatment arms and agents.

DRUG

Eloralintide

Administered SC.

Timeline

From registration to results.

  1. First posted

    Jul 14, 2026

  2. Study start

    Jul 2026

  3. Primary completion

    Oct 2026

  4. Study completion

    Oct 2026

  5. Results posted

    Not reported

  6. Registry updated

    Jul 14, 2026

Outcomes

What the study measures.

Primary outcomes

Pharmacokinetics (PK): Area Under the Concentration Versus Time Curve (AUC) of Eloralintide

Time frame · Predose on Day 1 through Day 57

PK: Maximum Concentration (Cmax) of Eloralintide

Time frame · Predose on Day 1 through Day 57

Secondary outcomes

Not reported in the indexed record.

Eligibility

Who can take part.

Minimum age
18 Years
Maximum age
65 Years
Sex
ALL
Healthy volunteers
Yes

Inclusion Criteria: * Are overtly healthy as determined by medical evaluation * Have a body mass index (BMI) within the range of 20.0 to 32.0 kilogram per square meter (kg/m2), inclusive Exclusion Criteria: * Have known allergies to related compounds of eloralintide, or any of the components of the formulations * Have significant previous or current history of comorbidities capable of significantly altering the absorption, metabolism, or elimination of drugs; of constituting a risk when taking the investigational product; or of interfering with the interpretation of data * Have been diagnosed with Type 1 or Type 2 diabetes mellitus, or have glycated hemoglobin greater than or equal to 6.5% or 48 millimole per mole (mmol/mol) * Have a history of any malignancy within the past 5 years except for basal cell or squamous epithelial carcinomas of the skin that have been resected with no evidence of metastatic disease for 3 years * Have a history or presence of a gastrointestinal (GI) disorder or previous surgery that impacts gastric emptying for example, gastric bypass surgery or pyloric stenosis * Have obesity induced by other endocrinologic disorders for example, Cushing syndrome, or diagnosed monogenetic or syndromic forms of obesity for example, Melanocortin 4 Receptor deficiency or Prader Willi syndrome * Have taken approved or investigational medication for weight loss, including glucagon-like peptide-1 receptor agonists (GLP-1 RAs), within the previous 3 months of study screening * Intend to use any weight loss medications during study participation

Study locations

2 registered sites.

United States. Showing up to 24 locations stored in the fast local snapshot.

Fortrea Clinical Research Unit

Daytona Beach, Florida, United States

Fortrea Clinical Research Unit

Dallas, Texas, United States

Publications

Results and literature.

No PMID-linked publications were present in this registry snapshot.

Primary links

Continue at the source.

Related trials

More studies on Eloralintide.

Related PeptideStat pages

Put the record in context.

Research pages describe evidence. Vendor pages, where available, describe independently tracked research-product listings and are not clinical recommendations.