DRUG
Eloralintide
Administered SC.
Status
Not yet recruiting
Phase
Phase 1
Enrollment
58
Locations
2
Results
Not posted
Publications
0
Study summary
The main purpose of this study is to learn about safety, tolerability and how well the body processes two different eloralintide solutions. Participation in this study will last about 13 weeks, including screening, inpatient treatment, and follow-up.
Interventions
DRUG
Administered SC.
Timeline
First posted
Jul 14, 2026
Study start
Jul 2026
Primary completion
Oct 2026
Study completion
Oct 2026
Results posted
Not reported
Registry updated
Jul 14, 2026
Outcomes
Pharmacokinetics (PK): Area Under the Concentration Versus Time Curve (AUC) of Eloralintide
Time frame · Predose on Day 1 through Day 57
PK: Maximum Concentration (Cmax) of Eloralintide
Time frame · Predose on Day 1 through Day 57
Not reported in the indexed record.
Eligibility
Inclusion Criteria: * Are overtly healthy as determined by medical evaluation * Have a body mass index (BMI) within the range of 20.0 to 32.0 kilogram per square meter (kg/m2), inclusive Exclusion Criteria: * Have known allergies to related compounds of eloralintide, or any of the components of the formulations * Have significant previous or current history of comorbidities capable of significantly altering the absorption, metabolism, or elimination of drugs; of constituting a risk when taking the investigational product; or of interfering with the interpretation of data * Have been diagnosed with Type 1 or Type 2 diabetes mellitus, or have glycated hemoglobin greater than or equal to 6.5% or 48 millimole per mole (mmol/mol) * Have a history of any malignancy within the past 5 years except for basal cell or squamous epithelial carcinomas of the skin that have been resected with no evidence of metastatic disease for 3 years * Have a history or presence of a gastrointestinal (GI) disorder or previous surgery that impacts gastric emptying for example, gastric bypass surgery or pyloric stenosis * Have obesity induced by other endocrinologic disorders for example, Cushing syndrome, or diagnosed monogenetic or syndromic forms of obesity for example, Melanocortin 4 Receptor deficiency or Prader Willi syndrome * Have taken approved or investigational medication for weight loss, including glucagon-like peptide-1 receptor agonists (GLP-1 RAs), within the previous 3 months of study screening * Intend to use any weight loss medications during study participation
Study locations
United States. Showing up to 24 locations stored in the fast local snapshot.
Fortrea Clinical Research Unit
Daytona Beach, Florida, United States
Fortrea Clinical Research Unit
Dallas, Texas, United States
Publications
No PMID-linked publications were present in this registry snapshot.
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