Eptifibatide for Extended Window Ischemic Stroke After Thrombolysis
Xinqiao Hospital of Chongqing · Acute Ischemic Stroke
Phase 3
Not yet recruiting
786
2026-01
Evidence dashboardStudies since 2003Updated Jul 31, 2026
EptifibatideClinical Trials.
A source-linked view of every Eptifibatide study in the current snapshot—status, phase, enrollment, results, publications, locations and changes over time.
- Total trials
- 35
- Recruiting
- 0
- Completed
- 21
- Terminated
- 6
- Results posted
- 14
- Average enrollment
- 1,278
- Countries
- 59
- Highest phase
- Phase 4
Largest indexed study
13,220 participants · NCT01076764 →Developer / research origin
Millennium Pharmaceuticals
Evidence summary
Activity is not efficacy.
Eptifibatide appears in 35 indexed studies: 0 recruiting, 21 completed and 14 with registry results posted. The highest registered development stage in this snapshot is Phase 4. These counts measure registry activity; they do not establish that Eptifibatide is safe or effective.
Review the design, endpoints, population, protocol changes, statistical analysis and publications before drawing conclusions.
Current studies
Recruiting or active
Completed studies
Finished records
Stopped studies
Withdrawn or terminated
NCT IDStudyPhase / statusEnrollmentUpdated
NCT IDStudyPhase / statusEnrollmentUpdated
Multi-arm Optimization of Stroke Thrombolysis
Washington University School of Medicine · Acute Ischemic Stroke
Phase 3
Completed
514
2025-02
EARLY ACS: Early Glycoprotein IIb/IIIa Inhibition in Patients With Non-ST-segment Elevation Acute Coronary Syndrome (Study P03684AM2)(COMPLETED)
Organon and Co · Myocardial Ischemia · Acute Coronary Syndrome
Phase 3
Completed
9,406
2024-05
Shortened Aggrastat® Versus Integrilin in Percutaneous Coronary Intervention
Medicure · Myocardial Infarction · Acute Coronary Syndromes
Phase 2
Completed
535
2021-05
Crushed Ticagrelor Versus Eptifibatide Bolus + Clopidogrel
University of Alabama at Birmingham · Acute Coronary Syndrome · Angina, Unstable
Phase 2
Completed
100
2020-05
Aspirin Resistance and Percutaneous Coronary Intervention (PCI)
Icahn School of Medicine at Mount Sinai · Stable Angina
Phase 2
Completed
36
2018-02
Co-administration of Iloprost and Eptifibatide in Septic Shock Patients
Sisse R. Ostrowski, MD PhD DMSc · Septic Shock
Phase 2
Completed
18
2017-04
Showing 6 of 21 studies
NCT IDStudyPhase / statusEnrollmentUpdated
Should Integrilin be an Integral Part of Adjunctive Therapy in Patients Undergoing Primary PCI for ST-Elevation MI?
Medstar Health Research Institute · ST-elevation Myocardial Infarction · Acute Myocardial Infarction
Not applicable
Withdrawn
0
2021-07
Integrilin and Ilomedin in Combination in Comparison to Standard Treatment in Severe Pneumonia Patients With Severe Sepsis
Thrombologic ApS · Pneumonia
Phase 2
Terminated
5
2016-04
Eptifibatide and ST Segment Resolution Following Primary PCI
Medstar Health Research Institute · Myocardial Infarction
Phase 3
Terminated
22
2014-08
A Safety Study of Eptifibatide in Patients With Sickle Cell Disease
University of North Carolina, Chapel Hill · Sickle Cell Disease
Phase 1 / Phase 2
Terminated
13
2013-06
A Safety/Efficacy Study of Intracoronary Integrilin to Improve Balloon Angioplasty Outcomes for the Treatment of Heart Attacks
Brigham and Women's Hospital · ST-Elevation Myocardial Infarction
Phase 2
Terminated
31
2012-08
The INtegrilin Plus STenting to Avoid Myocardial Necrosis Trial (INSTANT)
University of Turin, Italy · Coronary Artery Disease
Phase 4
Terminated
91
2011-10
Showing 6 of 7 studies
Full study index
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Add status, phase, condition, country, result and publication filters inside this molecule’s indexed study set.
35 matching studies
Last registry update first
Latest publications
Follow the paper trail.
PMID 3201508 ↗Bonita R, Beaglehole R. Recovery of motor function after stroke. Stroke. 1988 Dec;19(12):1497-500. doi: 10.1161/01.str.19.12.1497.Linked from NCT07347626PMID 33427887 ↗Seners P, Ben Hassen W, Lapergue B, Arquizan C, Heldner MR, Henon H, Perrin C, Strambo D, Cottier JP, Sablot D, Girard Buttaz I, Tamazyan R, Preterre C, Agius P, Laksiri N, Mechtouff L, Bejot Y, Duong DL, Mounier-Vehier F, Mione G, Rosso C, Lucas L, Papassin J, Aignatoaie A, Triquenot A, Carrera E, Niclot P, Obadia A, Lyoubi A, Garnier P, Crainic N, Wolff V, Tracol C, Philippeau F, Lamy C, Soize S, Baron JC, Turc G; MINOR-STROKE Collaborators. Prediction of Early Neurological Deterioration in Individuals With Minor Stroke and Large Vessel Occlusion Intended for Intravenous Thrombolysis Alone. JAMA Neurol. 2021 Mar 1;78(3):321-328. doi: 10.1001/jamaneurol.2020.4557.Linked from NCT07347626PMID 36711206 ↗Han L, Hou Z, Ma M, Ding D, Wang D, Fang Q. Impact of glycosylated hemoglobin on early neurological deterioration in acute mild ischemic stroke patients treated with intravenous thrombolysis. Front Aging Neurosci. 2023 Jan 12;14:1073267. doi: 10.3389/fnagi.2022.1073267. eCollection 2022.Linked from NCT07347626PMID 33296224 ↗Yang T, Fan K, Cao Y, Yan J, Han Z. Stroke Type, Etiology, Clinical Features and Prognosis of Diabetic Patients in Southern China. Clin Appl Thromb Hemost. 2020 Jan-Dec;26:1076029620973090. doi: 10.1177/1076029620973090.Linked from NCT07347626PMID 34329730 ↗Tu WJ, Chao BH, Ma L, Yan F, Cao L, Qiu H, Ji XM, Wang LD. Case-fatality, disability and recurrence rates after first-ever stroke: A study from bigdata observatory platform for stroke of China. Brain Res Bull. 2021 Oct;175:130-135. doi: 10.1016/j.brainresbull.2021.07.020. Epub 2021 Jul 27.Linked from NCT07347626PMID 35130717 ↗Wang M, Wang CJ, Gu HQ, Meng X, Jiang Y, Yang X, Zhang J, Xiong YY, Zhao XQ, Liu LP, Wang YL, Wang YJ, Li ZX. Sex Differences in Short-Term and Long-Term Outcomes Among Patients With Acute Ischemic Stroke in China. Stroke. 2022 Jul;53(7):2268-2275. doi: 10.1161/STROKEAHA.121.037121. Epub 2022 Feb 8.Linked from NCT07347626PMID 28052979 ↗Wang W, Jiang B, Sun H, Ru X, Sun D, Wang L, Wang L, Jiang Y, Li Y, Wang Y, Chen Z, Wu S, Zhang Y, Wang D, Wang Y, Feigin VL; NESS-China Investigators. Prevalence, Incidence, and Mortality of Stroke in China: Results from a Nationwide Population-Based Survey of 480 687 Adults. Circulation. 2017 Feb 21;135(8):759-771. doi: 10.1161/CIRCULATIONAHA.116.025250. Epub 2017 Jan 4.Linked from NCT07347626PMID 34838189 ↗The Lancet Public Health. Strengthening public health for a Healthy China. Lancet Public Health. 2021 Dec;6(12):e866. doi: 10.1016/S2468-2667(21)00261-9. No abstract available.Linked from NCT07347626
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