PRIMARY-HF: Heart Failure Screening in Primary Care Using Point-of- Care
Universidade do Porto · Heart Failure
Not applicable
Recruiting
160
2026-07
Evidence dashboardStudies since 2002Updated Jul 31, 2026
NesiritideClinical Trials.
A source-linked view of every Nesiritide study in the current snapshot—status, phase, enrollment, results, publications, locations and changes over time.
- Total trials
- 75
- Recruiting
- 17
- Completed
- 28
- Terminated
- 5
- Results posted
- 7
- Average enrollment
- 339
- Countries
- 40
- Highest phase
- Phase 4
Largest indexed study
20,000 participants · NCT05812248 →Developer / research origin
Johnson & Johnson
Evidence summary
Activity is not efficacy.
Nesiritide appears in 75 indexed studies: 17 recruiting, 28 completed and 7 with registry results posted. The highest registered development stage in this snapshot is Phase 4. These counts measure registry activity; they do not establish that Nesiritide is safe or effective.
Review the design, endpoints, population, protocol changes, statistical analysis and publications before drawing conclusions.
Current studies
Recruiting or active
Completed studies
Finished records
Stopped studies
Withdrawn or terminated
NCT IDStudyPhase / statusEnrollmentUpdated
Boston Medical Center Ultrasound Decongestion Study in Heart Failure
Boston Medical Center · Congestive Heart Failure · Volume Overload
Not applicable
Not yet recruiting
200
2026-06
Measurement Of NT-proBNP to Predict Outcomes in Surgery
Norfolk and Norwich University Hospitals NHS Foundation Trust · Vascular Surgical Procedure
Not applicable
Recruiting
200
2026-06
rhBNP for Prevention of Cardiac Surgery-Associated Acute Kidney Injury (CSA-AKI)
China National Center for Cardiovascular Diseases · AKI - Acute Kidney Injury · Cardiac Surgical Procedures
Phase 4
Not yet recruiting
694
2026-06
Utilising AI Analysis of Sounds To prEdict heaRt failurE decOmpensation
Cambridge University Hospitals NHS Foundation Trust · Heart Failure
Not applicable
Recruiting
250
2026-05
Better Understanding of Fatigue After STroke
Brugmann University Hospital · Stroke
Not applicable
Recruiting
250
2026-03
Showing 6 of 31 studies
NCT IDStudyPhase / statusEnrollmentUpdated
Venous Excess and Lung Ultrasound During Continuous Kidney Replacement Therapy in Critically Ill Patients
Chulalongkorn University · Acute Kidney Failure Stage 3
Not applicable
Completed
100
2026-05
Spironolactone Therapy in Chronic Stable Right HF Trial
Ottawa Heart Institute Research Corporation · Chronic Right-Sided Heart Failure · Pulmonary Arterial Hypertension
Phase 4
Completed
15
2026-05
Secondary Use of PARALLEL-HF Data
Novartis · Chronic Heart Failure and Reduced Ejection Fraction (HFrEF)
Not applicable
Completed
236
2026-04
Neural Respiratory Drive Combined With Pro-Brain Natriuretic Peptide (Pro-BNP) as Predictor of Deterioration After Lung Transplantation
The First Affiliated Hospital of Guangzhou Medical University · Lung Transplantation
Not applicable
Completed
80
2026-04
Serial Measurement of Pancreatic Stone Protein (PSP) for Sepsis Early Detection in ICU Patients
Fapon Biotech Inc. · Adult Patients at High Risk of Sepsis
Not applicable
Completed
250
2025-11
Natriuretic Peptide Concentrations of B-type (BNP) During Anesthesia in Patients Previously Sensitized to Anthracyclines
Institut Bergonié · Breast Cancer
Not applicable
Completed
54
2025-10
Showing 6 of 28 studies
NCT IDStudyPhase / statusEnrollmentUpdated
A Study of Ponsegromab in People With Heart Failure
Pfizer · Heart Failure
Phase 2
Terminated
455
2026-03
REGN5381 in Adult Participants With Heart Failure With Reduced Ejection Fraction
Regeneron · Heart Failure
Phase 2
Terminated
89
2026-01
Mechanism(s) Underlying Hypotensive Response to ARB/NEP Inhibition - Aim 1
Vanderbilt University Medical Center · Hypertension
Phase 4
Terminated
4
2025-08
Metabolic Effects of Natriuretic Peptide Hormones
VA Office of Research and Development · Obesity · Cardiovascular Physiological Phenomena
Phase 4
Terminated
5
2024-11
Reversible Pulmonary Artery Banding as Simplified Management of End-stage Dilated Left Ventriculopathy in Early Life
Loma Linda University · Acute on Chronic Systolic Congestive Heart Failure
Not applicable
Terminated
4
2023-02
Full study index
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75 matching studies
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Latest publications
Follow the paper trail.
PMID 17525578 ↗Augoustides J, Fleisher LA. Advancing perioperative prediction of cardiac risk after vascular surgery: does postoperative N-terminal pro-brain natriuretic peptide do the trick? Anesthesiology. 2007 Jun;106(6):1080-2. doi: 10.1097/01.anes.0000267586.04132.65. No abstract available.Linked from NCT04014647PMID 16055493 ↗Bursi F, Babuin L, Barbieri A, Politi L, Zennaro M, Grimaldi T, Rumolo A, Gargiulo M, Stella A, Modena MG, Jaffe AS. Vascular surgery patients: perioperative and long-term risk according to the ACC/AHA guidelines, the additive role of post-operative troponin elevation. Eur Heart J. 2005 Nov;26(22):2448-56. doi: 10.1093/eurheartj/ehi430. Epub 2005 Jul 29.Linked from NCT04014647PMID 26231089 ↗Canavan M, Smyth A, Robinson SM, Gibson I, Costello C, O'Keeffe ST, Walsh T, Mulkerrin EC, O'Donnell MJ. Attitudes to outcomes measured in clinical trials of cardiovascular prevention. QJM. 2016 Jun;109(6):391-7. doi: 10.1093/qjmed/hcv132. Epub 2015 Jul 31.Linked from NCT04014647PMID 16914484 ↗Feringa HH, Schouten O, Dunkelgrun M, Bax JJ, Boersma E, Elhendy A, de Jonge R, Karagiannis SE, Vidakovic R, Poldermans D. Plasma N-terminal pro-B-type natriuretic peptide as long-term prognostic marker after major vascular surgery. Heart. 2007 Feb;93(2):226-31. doi: 10.1136/hrt.2006.093716. Epub 2006 Aug 16.Linked from NCT04014647PMID 17525582 ↗Mahla E, Baumann A, Rehak P, Watzinger N, Vicenzi MN, Maier R, Tiesenhausen K, Metzler H, Toller W. N-terminal pro-brain natriuretic peptide identifies patients at high risk for adverse cardiac outcome after vascular surgery. Anesthesiology. 2007 Jun;106(6):1088-95. doi: 10.1097/01.anes.0000267591.34626.b0.Linked from NCT04014647PMID 16979009 ↗van Kimmenade RR, Januzzi JL Jr, Ellinor PT, Sharma UC, Bakker JA, Low AF, Martinez A, Crijns HJ, MacRae CA, Menheere PP, Pinto YM. Utility of amino-terminal pro-brain natriuretic peptide, galectin-3, and apelin for the evaluation of patients with acute heart failure. J Am Coll Cardiol. 2006 Sep 19;48(6):1217-24. doi: 10.1016/j.jacc.2006.03.061. Epub 2006 Aug 28.Linked from NCT04014647PMID 15997451 ↗Yeh HM, Lau HP, Lin JM, Sun WZ, Wang MJ, Lai LP. Preoperative plasma N-terminal pro-brain natriuretic peptide as a marker of cardiac risk in patients undergoing elective non-cardiac surgery. Br J Surg. 2005 Aug;92(8):1041-5. doi: 10.1002/bjs.4947.Linked from NCT04014647PMID 24247300 ↗Chen HH, Anstrom KJ, Givertz MM, Stevenson LW, Semigran MJ, Goldsmith SR, Bart BA, Bull DA, Stehlik J, LeWinter MM, Konstam MA, Huggins GS, Rouleau JL, O'Meara E, Tang WH, Starling RC, Butler J, Deswal A, Felker GM, O'Connor CM, Bonita RE, Margulies KB, Cappola TP, Ofili EO, Mann DL, Davila-Roman VG, McNulty SE, Borlaug BA, Velazquez EJ, Lee KL, Shah MR, Hernandez AF, Braunwald E, Redfield MM; NHLBI Heart Failure Clinical Research Network. Low-dose dopamine or low-dose nesiritide in acute heart failure with renal dysfunction: the ROSE acute heart failure randomized trial. JAMA. 2013 Dec 18;310(23):2533-43. doi: 10.1001/jama.2013.282190.Linked from NCT07617675
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