Brain and focus
Cognitive Peptides
Cognitive peptides are often marketed for focus, mood or neuroprotection, but the evidence base is uneven and often regional. The strongest claims need careful source checking.
- Peptides covered
- 2
- Highest evidence
- 3/5
- Approved entries
- 0
How to compare this category
Use this category hub to compare Selank and Semax by route, evidence score, mechanism and the gap between regional use and broadly validated human data.
- Distinguish regional clinical history from large independent randomized trials.
- Check whether the outcome is anxiety, neuroprotection, cognition or a broader marketing claim.
- Be careful with nootropic claims when the evidence is mainly mechanistic or preclinical.
Evidence scale
Scores rate evidence quality for the listed research context. They are not recommendations, prescriptions or a safety ranking.
- Evidence 1/5
- Mechanistic rationale only; no meaningful outcome evidence.
- Evidence 2/5
- Mostly animal, ex vivo, cell, or indirect evidence.
- Evidence 3/5
- Limited human pharmacology or small clinical evidence.
- Evidence 4/5
- Investigational compound with human randomized or phase 2/3 evidence.
- Evidence 5/5
- Approved medication with substantial human clinical evidence.
| Peptide | Status | Evidence | Best for | Half-life | Actions |
|---|---|---|---|---|---|
| Selank Synthetic tuftsin analog | Research only | 3/5 Limited human and mechanistic evidence | Anxiolytic and stress-response research context Limited human and mechanistic evidence | Minutes | |
| Semax Synthetic ACTH analog | Research only | 2/5 Mostly preclinical neuroprotection evidence | Neuroprotection and ACTH-fragment research context Mostly preclinical evidence for broad consumer claims | Minutes |
Cognitive peptide cards
Cognitive guides
Read the strongest related guides for this category before drilling into a single database entry.
FAQ
What are cognitive peptides?
Cognitive peptides are neuropeptides or peptide analogs discussed for mood, focus, anxiety or neuroprotection. Evidence quality varies by compound and claim.
Is Selank better studied than Semax?
In this database, Selank has a slightly higher evidence score because it has small clinical comparison literature plus mechanistic work, while Semax claims rely more heavily on preclinical neuroprotection evidence.
Are cognitive peptides approved in the United States?
The cognitive peptides listed here are treated as research-only for US consumer purposes and do not have approved US indications.
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