Selank
Also known as: TP-7
Russian-developed analog of tuftsin marketed (in Russia) as an anxiolytic. Mechanism involves modulation of GABA and stress-response pathways.
- Drug class
- Synthetic tuftsin analog
- Primary targets
- GABAergic / serotonergic systems
- Dose reference
- 150–500 mcg per dose (intranasal, research)
- Half-life
- Minutes
- Developer / origin
- Russian Academy of Sciences
- Reference year
- 1990
- Evidence score
- 3/5 - Limited human and mechanistic evidence
Limited human and mechanistic evidence
Selank has small Russian clinical literature and mechanistic/anxiolytic studies, but lacks broad Western regulatory review or large independent trials.
Limited human pharmacology or small clinical evidence.
Evidence basis
- Small clinical comparison literature
- Mechanistic anxiolytic reviews
- Preclinical stress/anxiety models
How to read this entry
Dose references and half-life values are pulled from trial protocols, labels, reviews, or published summaries where available. They are context for research and comparison, not a personal dosing recommendation.
Status matters: approved drugs have regulated indications; investigational compounds are still being studied; research-only peptides do not have established human dosing, safety, or efficacy for consumer use.
Selank guides
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Compare with related peptides
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N-Acetyl Semax Amidate, NA Semax
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N-Acetyl Selank
NA Selank Amidate
N-Acetyl Selank is a chemically stabilized (N-acetylated, C-amidated) analog of the tuftsin-derived peptide Selank, proposed to act via GABAergic modulation, inhibition of enkephalin-degrading enzymes that raises endogenous enkephalins, and BDNF-related effects, though these mechanisms were demonstrated for the parent Selank rather than the analog.
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