Bryan Johnson Hair Protocol: Peptide Shampoo, Serum, Laser Cap & Minoxidil

This Bryan Johnson hair protocol keeps the order simple: clean the scalp, apply the peptide products, use light therapy consistently, and keep minoxidil as the medical hair-growth layer when it is appropriate for you.

The Blueprint product buttons use the recommendation link and may show $25 off at checkout when eligible. For the dedicated coupon page, see the Bryan Johnson discount code guide. For a broader evidence map, see best peptides for hair growth. For the shampoo-specific breakdown, see peptide shampoo.

Protocol Order

Order	Step	Use
1	Peptide Shampoo	Use as the scalp prep/treatment step in the shower. Massage into the scalp, leave for about 2 minutes, then rinse.
2	Peptide Hair Serum	Apply to a dry scalp, focus on thinning areas, massage in, and let it dry before styling products.
3	302 Laser Cap	Use on dry hair/scalp for 6 minutes daily. Blueprint's public protocol uses the cap after the serum.
4	Minoxidil	Use topical minoxidil according to the product label or prescription plan. Oral minoxidil is prescription/off-label for hair and needs clinician guidance.

Step 1

Blueprint Peptide Shampoo

$25 off

This is the rinse-off scalp step. It combines gentle cleansers with peptides, caffeine, adenosine, copper tripeptide, niacinamide, panthenol, amino acids, and antioxidants.

View shampoo

Ingredient	Role
Aqua	Water base and solvent.
Lauryl Glucoside	Gentle non-ionic cleanser.
Glycerin	Humectant that helps hold water on the scalp and hair.
Decyl Glucoside	Mild cleanser and foam support.
Coco-Glucoside	Mild cleanser that helps lift oil and buildup.
Disodium Lauryl Sulfosuccinate	Mild anionic cleanser for foam and rinse-off cleansing.
Pentylene Glycol	Humectant, solvent, and preservation support.
Lauramidopropyl Betaine	Foam booster and co-surfactant that can make cleansing feel less harsh.
Sodium Cocoyl Apple Amino Acids	Amino-acid-derived surfactant for gentle cleansing.
Betaine	Humectant/osmolyte that supports scalp comfort.
Glycol Distearate	Pearlizing and conditioning ingredient that improves texture.
Polyquaternium-10	Conditioning polymer for slip and smoother-feeling hair.
Caprylyl/Capryl Glucoside	Solubilizer and gentle cleanser.
sh-Oligopeptide-1	EGF-style biomimetic peptide for cosmetic scalp conditioning.
sh-Oligopeptide-4	Biomimetic peptide used for scalp and skin conditioning.
sh-Polypeptide-1	Biomimetic peptide for cosmetic scalp-support signaling.
sh-Polypeptide-7	Biomimetic peptide used for scalp conditioning.
sh-Polypeptide-9	VEGF-style biomimetic peptide for scalp hydration and conditioning claims.
sh-Polypeptide-11	Biomimetic peptide for cosmetic conditioning.
sh-Polypeptide-71	Biomimetic peptide for cosmetic conditioning.
Copper Tripeptide-1	Copper peptide used for scalp conditioning, antioxidant support, and repair-signaling cosmetics.
Niacinamide	Vitamin B3 for barrier support, oil balance, and scalp comfort.
3-O-Ethyl Ascorbic Acid	Vitamin C derivative for antioxidant support.
Adenosine	Hair-cycle-support ingredient with human topical data in androgenetic alopecia.
Caffeine	Scalp active with topical hair-growth data; contact time matters.
Arginine	Amino acid used for conditioning and formula pH/support.
Tetrahydrocurcumin	Curcumin-derived antioxidant.
Curcumin	Plant antioxidant for scalp comfort.
Menthol	Cooling scalp feel; possible irritant for sensitive scalps.
Silk Amino Acids	Humectant and hair-conditioning support.
Tetrasodium Glutamate Diacetate	Chelator that improves stability and preservative performance.
Mentha Arvensis Herb Oil	Mint-derived cooling/sensory ingredient; possible irritant for reactive scalps.
Lecithin	Phospholipid emulsifier and delivery support.
Trehalose	Humectant/osmoprotectant.
Glyceryl Caprylate	Emollient and preservative booster.
Hexylene Glycol	Solvent and texture support.
Panthenol	Provitamin B5 for moisture, shine, and conditioning.
Polysorbate 60	Emulsifier/solubilizer.
Citric Acid	pH adjuster.
Sodium Citrate	Buffer that helps keep pH stable.
Sodium Chloride	Viscosity control.
Phenoxyethanol	Preservative.
Limonene	Natural fragrance component/allergen from botanical materials.

Step 2

Blueprint Peptide Hair Serum

$25 off

This is the main leave-on peptide step. The serum has the stronger logic because it stays on the scalp instead of being rinsed away.

View serum

Ingredient	Role
Aqua	Water base and solvent.
Pentylene Glycol	Humectant, solvent, and preservative support.
Glycerin	Humectant that supports scalp hydration.
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer	Gel former and texture stabilizer.
sh-Oligopeptide-1	EGF-style biomimetic peptide for cosmetic scalp conditioning.
sh-Oligopeptide-4	Biomimetic peptide used for scalp conditioning.
sh-Polypeptide-4	Biomimetic peptide for cosmetic scalp-support signaling.
sh-Polypeptide-7	Biomimetic peptide used for scalp conditioning.
sh-Polypeptide-9	VEGF-style biomimetic peptide for scalp conditioning and vitality claims.
sh-Polypeptide-59	Biomimetic peptide for cosmetic scalp support.
sh-Polypeptide-86	Follistatin-style biomimetic peptide used for fuller, healthier-looking hair claims.
DNA / PDRN	Nucleotide-based ingredient tied to repair-signaling research, mostly outside simple leave-on cosmetics.
Nicotinamide Mononucleotide	NMN; antioxidant/cellular-energy cosmetic positioning.
Curcumin	Plant antioxidant for scalp comfort.
Tetrahydrocurcumin	Curcumin-derived antioxidant.
Copper Tripeptide-1	Copper peptide used for scalp conditioning and repair-signaling cosmetics.
Panthenol	Provitamin B5 for hydration, shine, and conditioning.
Caffeine	Hair-cycle-support active with topical research; stronger logic in leave-on products than rinse-off products.
Adenosine	Hair-cycle-support ingredient with human topical data.
Niacinamide	Vitamin B3 for barrier support and scalp comfort.
Arginine	Amino acid used for conditioning and formula support.
Ketoglutaric Acid	Metabolic intermediate and formula-support ingredient.
Salicylic Acid	Exfoliant that can help with scale, oil, and buildup.
Thioctic Acid	Alpha-lipoic-acid antioxidant.
Lecithin	Phospholipid emulsifier and delivery support.
1,2-Hexanediol	Humectant and preservative booster.
Acetyl Cysteine	Antioxidant support and glutathione precursor.
Glycine	Amino acid humectant/conditioning support.
3-O-Ethyl Ascorbic Acid	Vitamin C derivative for antioxidant support.
p-Anisic Acid	Preservative support and antimicrobial formula helper.
Polysorbate 60	Emulsifier/solubilizer.
Sodium Citrate	Buffer that helps keep pH stable.
Citric Acid	pH adjuster.
Glutathione	Antioxidant support.

Step 3

Blueprint 302 Laser Cap

$25 off

This is the light-therapy layer. Blueprint describes the device as an FDA-cleared 302-laser-diode cap for androgenetic pattern hair loss, used for 6 minutes daily on dry hair and scalp.

View laser cap

Spec / feature	Role
302 laser diodes	Full-scalp coverage for common pattern-loss zones such as hairline, crown, and part line.
655 nm red laser light	Low-level laser therapy wavelength used for hair-growth device protocols.
6 minutes daily	Short daily exposure target from Blueprint's instructions.
Dry scalp use	Keeps the laser session consistent and matches Blueprint's directions.
Device layer, not a topical	Works separately from shampoo, serum, and minoxidil; consistency is the main variable.

Minoxidil Layer

Minoxidil is not a peptide product, but it belongs in the protocol because it has direct human evidence for androgenetic alopecia. Blueprint's public protocol mentions topical minoxidil and oral minoxidil, but those are different risk categories.

Option	Role	Notes
Topical minoxidil	Evidence-backed hair-growth medication layer.	Use according to the label or a prescriber's instructions. Let it dry before layering other scalp products.
Prescription topical blends	Clinician-directed formulas may combine minoxidil with other actives.	Follow the exact dose and timing from the prescriber.
Oral minoxidil	Off-label systemic option for hair loss.	Requires clinician oversight because it can affect blood pressure, fluid retention, heart rate, and body-hair growth.

Evidence Map

Layer	Evidence	Read
Topical minoxidil	5% minoxidil RCT and DailyMed labeling.	Most evidence-backed layer in the protocol.
Laser cap / LLLT	Meta-analysis of randomized trials.	Reasonable adjunct for androgenetic hair loss when used consistently.
Caffeine	Topical caffeine vs minoxidil study.	Good active logic, especially in leave-on formulas.
Adenosine	Adenosine vs minoxidil study, topical adenosine trial, and adenosine complex study.	One of the better-supported cosmetic actives in the formula.
Copper tripeptide / GHK-Cu	GHK review and GHK-Cu delivery paper.	Interesting repair-signaling ingredient; finished-product hair-growth proof is limited.
PDRN	PRP plus PDRN hair-loss study.	Mechanistically interesting, but most hair data is not simple leave-on cosmetic use.
Follistatin-style peptides	Activin/follistatin hair-follicle biology review.	Supports the rationale, not a finished-product outcome claim.

Safety Rules

Patch test the shampoo and serum first. Stop if you get burning, rash, severe itching, or unusual shedding. Be careful with irritated, infected, painful, sunburned, or recently treated scalps.

See a dermatologist for sudden shedding, patchy hair loss, scalp pain, scarring, infection, or hair loss tied to a medication or medical condition. For oral minoxidil, prescription minoxidil blends, finasteride, or dutasteride, use clinician guidance.

FAQ

What is Bryan Johnson's hair protocol?

Bryan Johnson's public hair protocol combines scalp products, hair-growth medications, and device-based light therapy. This page focuses on the practical stack people usually mean when they search for the Bryan Johnson hair protocol: Blueprint Peptide Shampoo, Blueprint Peptide Hair Serum, the 302 Laser Cap, and minoxidil.

What products are in the Bryan Johnson hair protocol?

The core Blueprint hair products are Peptide Shampoo, Peptide Hair Serum, and the 302 Laser Cap. The broader protocol also references minoxidil as a hair-growth medication layer.

Does Bryan Johnson use minoxidil?

Bryan Johnson's public protocol references both topical minoxidil and oral minoxidil. Topical minoxidil is available over the counter in many markets. Oral minoxidil is prescription and off-label for hair loss, so it needs clinician guidance.

Does Blueprint Peptide Hair Serum replace minoxidil?

No. Blueprint's peptide shampoo and serum are cosmetic scalp products. They can fit next to minoxidil in a routine, but they should not be treated as direct replacements for proven hair-loss medications.

How often do you use the Blueprint 302 Laser Cap?

Blueprint's laser cap directions describe daily use on dry hair and scalp for 6 minutes. Consistency matters more than occasional long sessions.

Which matters more, the shampoo or the serum?

The serum is the stronger peptide step because it stays on the scalp. The shampoo can still be useful as scalp prep, but rinse-off products have less contact time.

Is there a Bryan Johnson discount code for the hair products?

The recommendation links may apply $25 off at checkout when eligible. The coupon-focused page is here: Bryan Johnson discount code.

References

1. Blueprint. Bryan Johnson's public protocol.

2. Blueprint. Peptide Shampoo product page.

3. Blueprint. Peptide Hair Serum product page.

4. Blueprint. 302 Laser Cap product page.

5. Olsen EA, et al. A randomized clinical trial of 5% topical minoxidil versus 2% minoxidil and placebo in men with androgenetic alopecia.

6. DailyMed. Minoxidil 5% topical solution labeling.

7. Adil A, Godwin M. Low-level laser therapy for androgenetic alopecia: a systematic review and meta-analysis.

8. JAMA Dermatology. Oral minoxidil versus topical minoxidil randomized trial.

9. Dhurat R, et al. Topical caffeine-based liquid versus minoxidil 5% in male androgenetic alopecia.

10. Faghihi G, et al. Topical adenosine versus minoxidil in male androgenetic alopecia.

11. Iwabuchi T, et al. Topical adenosine and thick hair ratio in Caucasian men with androgenetic alopecia.

12. Kim H, et al. Adenosine complex study for hair density and thickness.

13. Pickart L, Margolina A. GHK and copper peptide biology review.

14. Zhang Y, et al. GHK-Cu topical delivery paper.

15. Lee SH, et al. Platelet-rich plasma plus PDRN in female pattern hair loss.

16. McDowall M, et al. Activins and follistatins in skin and hair follicles.