PEPTIDESTAT
Research onlyHealing & recoverySubcutaneousEvidence 2/5

TB-500

Also known as: Thymosin Beta-4 fragment

Synthetic fragment of thymosin β4 studied in animal models for cell migration, angiogenesis and tissue repair. No approved human indication.

Read guideBuy / compare source
TB-500 product image
Drug class
Thymosin β4 derivative
Primary targets
G-actin
Dose reference
No human dosing established
Half-life
Not well characterized
Developer / origin
RegeneRx (related TB4 program)
Reference year
1981
Evidence score
2/5 - Indirect preclinical evidence
Evidence 2/5

Indirect preclinical evidence

TB-500 claims mostly rely on thymosin beta-4 repair biology and preclinical data rather than direct human TB-500 outcome trials.

Mostly animal, ex vivo, cell, or indirect evidence.

Evidence basis

  • Thymosin beta-4 repair biology
  • Preclinical repair literature
  • Weak direct human TB-500 evidence

How to read this entry

Dose references and half-life values are pulled from trial protocols, labels, reviews, or published summaries where available. They are context for research and comparison, not a personal dosing recommendation.

Status matters: approved drugs have regulated indications; investigational compounds are still being studied; research-only peptides do not have established human dosing, safety, or efficacy for consumer use.

TB-500 guides

Read the matching guide or adjacent research pages for more context.

BPC-157 vs TB-500: Which Recovery Peptide Has Better Evidence?BPC-157 and TB-500 are both marketed for recovery, but their evidence is mostly preclinical. Side by side, the real question is which one has even less human data.TB-500 Peptide: Thymosin Beta-4 Evidence and Safety LimitsTB-500 has a real thymosin beta-4 research trail behind it, but direct human recovery evidence for TB-500 protocols remains weak.BPC-157: Strong Animal Data, Almost No Human EvidenceBPC-157 is marketed hard for recovery and tissue repair. The animal data is genuinely interesting; the human data is almost entirely absent.Gut Health Peptides: Approved GI Drugs vs Research ClaimsGut peptide claims range from approved oral GI drugs to research-only BPC-157 and KPV. The evidence depends on route, target and endpoint.

TB-500 calculator shortcuts

Open peptide calculators with editable TB-500 example values already filled in.

TB-500 reconstitution calculatorPrefills a 5 mg vial, 2 mL BAC water and editable dose fields.Open prefilled toolTB-500 unit converterPrefills 2 mg with a 5 mg vial example.Open prefilled tool

Peptide calculators

Use calculators for concentration, unit conversion and repeated-dose accumulation math.

Peptide reconstitution calculatorCalculate concentration, draw volume and syringe units from vial strength and BAC water.Open toolPeptide accumulation calculatorModel repeated dosing schedules with half-life, interval, peak and trough estimates.Open toolPeptide unit converterConvert mg, mcg, optional IU and syringe units from one reconstituted vial setup.Open toolPeptide chemistry calculatorAnalyze sequence length, molecular weight, composition, charge, hydropathy and notation.Open tool

Compare with related peptides

Stay inside the same research category and compare mechanism, status and evidence quality.

BPC-157

Body Protection Compound-157

2/5
Healing & recoveryResearch only

Derived from human gastric juice. Animal models suggest effects on angiogenesis, tendon healing and GI repair; human clinical data is very limited.

DetailsGuide
3/5
Healing & recoveryResearch only

Thymosin beta-4 sequesters monomeric G-actin to regulate the actin cytoskeleton, enabling cell migration, angiogenesis and tissue repair, with an anti-fibrotic Ac-SDKP fragment.

DetailsGuide
2/5
Healing & recoveryInvestigational

VIP activates VPAC1 and VPAC2 receptors, raising intracellular cyclic AMP to drive vasodilation, smooth-muscle relaxation and immune modulation.

DetailsGuide

Category hub

Open the category page for the full comparison table and FAQ.

Healing Peptides

Compare healing peptides such as BPC-157 and TB-500 by evidence quality, mechanism, research status and practical limitations.

Research & educational purposes only

The information on PeptideStat is for educational and research purposes only and is not medical advice. Many peptides discussed are research compounds not approved for human use. Always consult a qualified healthcare professional before making any health decisions. Articles may contain affiliate links — we may earn a commission at no extra cost to you.