A Study to Characterize Regimens of Basal Insulin Intensified With Either Symlin® or Rapid Acting Insulin in Patients With Type 2 Diabetes

The Percentage of Patients Achieving HbA1c <=7% at Week 24 With no Gain in Body Weight From Baseline and no Incidence of Severe Hypoglycemia

Time frame · 24 Weeks

A severe hypoglycemia is defined as an event during which the patient required the assistance of another individual (including aid in ingestion of oral carbohydrate); and/or required the administration of glucagon injection, intravenous glucose, or other medical intervention.

Percentage of Patients Achieving HbA1c <=7% at Week 24

Time frame · 24 Weeks

This is a component of the primary endpoint

Percentage of Patients With no Weight Gain at Week 24

Time frame · 24 Weeks

This is a component of the primary endpoint

Percentage of Patients With a Severe Hypoglycemia Adverse Event

Time frame · 24 Weeks

This is a component of the primary endpoint.

Change in HbA1c From Baseline at Week 24

Time frame · From Baseline to Week 24

Baseline values are presented in the Baseline Characteristics section

Change in Body Weight From Baseline at Week 24

Time frame · From Baseline to Week 24

Baseline values are presented in the Baseline Characteristics section

Change in Waist Circumference From Baseline at Week 24

Time frame · From Baseline to Week 24

Baseline values are presented in the Baseline Characteristics section

Change in Fasting Plasma Glucose From Baseline at Week 24

Time frame · From Baseline to Week 24

Baseline values are presented in the Baseline Characteristics section

Fasting Serum Lipids Change From Baseline to Week 24

Time frame · Baseline, week 24

Phase 2: Change in HbA1c at Week 36

Time frame · Phase 1 Baseline, Phase 2 Baseline at Week 24, Week 36

Two changes are calculated, the first by subtracting Week 36 value from the Phase 1 Baseline value (total change over 36 weeks), the second by subtracting the Week 36 value from the Phase 2 Baseline value (change from week 24 to week 36 only).

Phase 2: Change in Body Weight at Week 36

Time frame · Phase 1 Baseline, Phase 2 Baseline at Week 24, Week 36

Two changes are calculated, the first by subtracting Week 36 value from the Phase 1 Baseline value (total change over 36 weeks), the second by subtracting the Week 36 value from the Phase 2 Baseline value (change from week 24 to week 36 only).