Postprandial Regulation of Bone Perfusion in Healthy Individuals
University of Copenhagen · Healthy Adult Participants · Bone Physiology
Not applicable
Not yet recruiting
15
2026-07
Evidence dashboardStudies since 2002Updated Jul 31, 2026
PramlintideClinical Trials.
A source-linked view of every Pramlintide study in the current snapshot—status, phase, enrollment, results, publications, locations and changes over time.
- Total trials
- 64
- Recruiting
- 1
- Completed
- 44
- Terminated
- 4
- Results posted
- 15
- Average enrollment
- 74
- Countries
- 5
- Highest phase
- Phase 4
Largest indexed study
1,297 participants · NCT00229658 →Developer / research origin
Amylin Pharmaceuticals
Evidence summary
Activity is not efficacy.
Pramlintide appears in 64 indexed studies: 1 recruiting, 44 completed and 15 with registry results posted. The highest registered development stage in this snapshot is Phase 4. These counts measure registry activity; they do not establish that Pramlintide is safe or effective.
Review the design, endpoints, population, protocol changes, statistical analysis and publications before drawing conclusions.
Current studies
Recruiting or active
Completed studies
Finished records
Stopped studies
Withdrawn or terminated
NCT IDStudyPhase / statusEnrollmentUpdated
Multi-Center Development of a Novel Diagnostic Test for Alzheimer's Disease
Boston University · Alzheimer Disease · Mild Cognitive Impairment
Early Phase 1
Active, not recruiting
57
2026-05
Pancreatic Polypeptide as a Modulator of Amylin- Induced Satiety in Healthy Humans
University Hospital, Gentofte, Copenhagen · Obesity & Overweight
Not applicable
Recruiting
18
2026-04
Hypersensitivity to Amylin in Post-Traumatic Headache
Danish Headache Center · Headache Disorders, Secondary · Brain Diseases
Not applicable
Not yet recruiting
21
2026-01
Amylin-Induced Migraine Attacks Without Aura
Danish Headache Center · Headache Disorders, Primary · Headache Disorders
Not applicable
Not yet recruiting
21
2026-01
NCT IDStudyPhase / statusEnrollmentUpdated
Two Way Crossover Closed Loop Study Insulin vs Insulin and Pramlintide
Oregon Health and Science University · Type 1 Diabetes
Not applicable
Completed
33
2026-06
Phase 2, Randomized, Open-Label, Crossover, PD/PK Study of a Novel Pram-Insulin Co-Formulation in Adults With T1D
Xeris Pharmaceuticals · Diabetes Mellitus, Type 1 · Insulin-dependent Diabetes Mellitus
Phase 2
Completed
18
2024-03
A Fully-closed Loop, Pramlintide and Insulin, Artificial Pancreas Clinical Trial for Adults With Type 1 Diabetes
McGill University Health Centre/Research Institute of the McGill University Health Centre · Type 1 Diabetes
Not applicable
Completed
12
2023-10
Pramlintide (Symlin) for the Treatment of Hypoglycemia Following Gastric Bypass Surgery
Joslin Diabetes Center · Hypoglycemia · Evidence of Previous Gastric Surgery
Phase 4
Completed
22
2023-06
Alleviating Carbohydrate Counting for Patients With Type 1 Diabetes Using a Novel Insulin-plus-pramlintide Artificial Pancreas
McGill University · Type 1 Diabetes · Type 1 Diabetes Mellitus
Not applicable
Completed
36
2022-10
Insulin-plus-pramlintide Closed-loop Strategy to Regulate Glucose Levels Without Carbohydrate Counting
McGill University · Diabetes Mellitus, Type 1
Phase 2
Completed
24
2021-06
Showing 6 of 44 studies
NCT IDStudyPhase / statusEnrollmentUpdated
Tailoring Obesity Treatment Trial
Esbjerg Hospital - University Hospital of Southern Denmark · Obesity · Appetite Regulation
Phase 2 / Phase 3
Withdrawn
0
2026-04
Biological Outcomes of Pramlintide in Resectable Cutaneous Squamous Cell Carcinoma: A Pilot Study
H. Lee Moffitt Cancer Center and Research Institute · Cutaneous Squamous Cell Carcinoma
Early Phase 1
Withdrawn
0
2023-06
Glucagon Counterregulation in Type 1 Diabetes
University of Virginia · Type 1 Diabetes Mellitus
Not applicable
Terminated
13
2022-03
Effects of Pramlintide on Endogenous Production of Very-low-density-lipoprotein (VLDL)-Triglyceride and Glucose in the Post Prandial State in T2DM
University of Maryland, Baltimore · Type 2 Diabetes
Not applicable
Withdrawn
0
2021-07
Safety Study of Using Symlin Alongside Insulin in a Multiple Injection Port
Texas Diabetes & Endocrinology, P.A. · Type 1 Diabetes · Type 2 Diabetes
Not applicable
Terminated
31
2020-10
Efficacy of Pramlintide on Prevention of Weight Gain Early Onset of Type 1 Diabetes
University of Texas Southwestern Medical Center · Type 1 Diabetes
Phase 4
Withdrawn
0
2019-01
Showing 6 of 9 studies
Full study index
Search Pramlintide trials.
Add status, phase, condition, country, result and publication filters inside this molecule’s indexed study set.
64 matching studies
Last registry update first
Latest publications
Follow the paper trail.
PMID 20194711 ↗Asmar M, Bache M, Knop FK, Madsbad S, Holst JJ. Do the actions of glucagon-like peptide-1 on gastric emptying, appetite, and food intake involve release of amylin in humans? J Clin Endocrinol Metab. 2010 May;95(5):2367-75. doi: 10.1210/jc.2009-2133. Epub 2010 Mar 1.Linked from NCT07340775PMID 26071095 ↗Hay DL, Chen S, Lutz TA, Parkes DG, Roth JD. Amylin: Pharmacology, Physiology, and Clinical Potential. Pharmacol Rev. 2015 Jul;67(3):564-600. doi: 10.1124/pr.115.010629.Linked from NCT07340775PMID 33772845 ↗Ghanizada H, Al-Karagholi MA, Walker CS, Arngrim N, Rees T, Petersen J, Siow A, Morch-Rasmussen M, Tan S, O'Carroll SJ, Harris P, Skovgaard LT, Jorgensen NR, Brimble M, Waite JS, Rea BJ, Sowers LP, Russo AF, Hay DL, Ashina M. Amylin Analog Pramlintide Induces Migraine-like Attacks in Patients. Ann Neurol. 2021 Jun;89(6):1157-1171. doi: 10.1002/ana.26072. Epub 2021 Apr 8.Linked from NCT07340775PMID 31527806 ↗Ashina H, Porreca F, Anderson T, Amin FM, Ashina M, Schytz HW, Dodick DW. Post-traumatic headache: epidemiology and pathophysiological insights. Nat Rev Neurol. 2019 Oct;15(10):607-617. doi: 10.1038/s41582-019-0243-8. Epub 2019 Sep 16.Linked from NCT07340775PMID 32102546 ↗Ashina H, Iljazi A, Al-Khazali HM, Ashina S, Jensen RH, Amin FM, Ashina M, Schytz HW. Persistent post-traumatic headache attributed to mild traumatic brain injury: Deep phenotyping and treatment patterns. Cephalalgia. 2020 May;40(6):554-564. doi: 10.1177/0333102420909865. Epub 2020 Feb 26.Linked from NCT07340775PMID 1603351 ↗Rasmussen BK, Olesen J. Symptomatic and nonsymptomatic headaches in a general population. Neurology. 1992 Jun;42(6):1225-31. doi: 10.1212/wnl.42.6.1225.Linked from NCT07340775PMID 34022171 ↗Ashina H, Eigenbrodt AK, Seifert T, Sinclair AJ, Scher AI, Schytz HW, Lee MJ, De Icco R, Finkel AG, Ashina M. Post-traumatic headache attributed to traumatic brain injury: classification, clinical characteristics, and treatment. Lancet Neurol. 2021 Jun;20(6):460-469. doi: 10.1016/S1474-4422(21)00094-6.Linked from NCT07340775PMID 20855363 ↗Hansen JM, Hauge AW, Olesen J, Ashina M. Calcitonin gene-related peptide triggers migraine-like attacks in patients with migraine with aura. Cephalalgia. 2010 Oct;30(10):1179-86. doi: 10.1177/0333102410368444. Epub 2010 May 12.Linked from NCT07340788
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