Safety and Efficacy of Abaloparatide-SC in Men With Osteoporosis (ATOM)

Percent Change From Baseline in Lumbar Spine BMD at Month 12

Time frame · Baseline, Month 12

Lumbar Spine BMD was assessed by DXA scans evaluated by a central imaging laboratory. Lumbar spine scans included L1 through L4. Positive changes from baseline indicate improvement in bone health.

Percent Change From Baseline in Total Hip BMD at Month 12

Time frame · Baseline, Month 12

Total hip BMD was assessed by DXA scans evaluated by a central imaging laboratory. Positive changes from baseline indicate improvement in bone health.

Percent Change From Baseline in Femoral Neck BMD at Month 12

Time frame · Baseline, Month 12

Femoral neck BMD was assessed by DXA scans evaluated by a central imaging laboratory. Positive changes from baseline indicate improvement in bone health.

Percent Change From Baseline in Lumbar Spine BMD at Month 6

Time frame · Baseline, Month 6

Lumbar Spine BMD was assessed by DXA scans evaluated by a central imaging laboratory. Lumbar spine scans included L1 through L4. Positive changes from baseline indicate improvement in bone health.

Percent Change in Total Hip BMD From Baseline at Month 6

Time frame · Baseline, Month 6

Total hip BMD was assessed by DXA scans evaluated by a central imaging laboratory. Positive changes from baseline indicate improvement in bone health.

Percent Change From Baseline in Femoral Neck BMD at Month 6

Time frame · Baseline, Month 6

Femoral neck BMD was assessed by DXA scans evaluated by a central imaging laboratory. Positive changes from baseline indicate improvement in bone health.

Percent Change From Baseline in Ultra-Distal Radius BMD at Month 12

Time frame · Baseline, Month 12

Ultra-distal radius BMD was assessed by DXA scans. Positive changes from baseline indicate improvement in bone health.

Percent Change From Baseline in Distal One-third Radius BMD at Month 12

Time frame · Baseline, Month 12

Distal one-third radius BMD was assessed by DXA scans. Positive changes from baseline indicate improvement in bone health.

Percent Change From Baseline in Serum Procollagen Type I N-terminal Propeptide (s-PINP) at Month 12

Time frame · Baseline, Month 12

Blood samples were taken to measure s-PINP, a bone formation marker. s-PINP concentrations reflect the rate of skeletal new bone formation. Increases in s-PINP indicate anabolic biologic response in the bone.

Percent Change From Baseline in Serum Carboxy-terminal Cross-linking Telopeptide of Type I Collagen (s-CTX) at Month 12

Time frame · Baseline, Month 12

Blood samples were taken to measure s-CTX. Elevated levels of s-CTX indicate increased bone resorption (bone loss).

Number of Participants With New Clinical Fractures

Time frame · Baseline through Month 12

Radiological evaluations were performed to identify any new clinical fractures (occurring after the screening visit).