DRUG
Carbetocin
carbetocin 100 mcg + RLS solution 10 ml injected directly into the vein over 2 min
Carbetocin Versus Oxytocin for Prevention of Postcesarean Hemorrhage in Pregnancy With High Risk for PPH
Status
Completed
Phase
Early Phase 1
Enrollment
120
Locations
1
Results
Not posted
Publications
0
Study summary
What the protocol is testing.
Objective: study efficacy of carbtocin versus oxytocin for prevention postpartum hemorrhage in high risk pregnancy who undergo cesarean section
Full detailed description
Randomized controlled clinical trial. Defined patient in two group. Primary outcome is evaluate additional drug use Secondary outcome is evaluated estimated blood loss, hemoglobin level
Interventions
Treatment arms and agents.
DRUG
oxytocin
oxytocin 20 IU diluted in 1000 ml of RLS solution administered intravenously at rate 120 ml/hr x 8 hr
Timeline
From registration to results.
First posted
Sep 13, 2019
Study start
Feb 1, 2019
Primary completion
Apr 30, 2019
Study completion
May 31, 2019
Results posted
Not reported
Registry updated
Sep 13, 2019
Outcomes
What the study measures.
Primary outcomes
Additional drug use
Time frame · during intra-operation
Number of additional drug use after intervention drug
Secondary outcomes
Estimate blood loss
Time frame · During intra-opeartion and acute post operation period as 24 hours post operation
amount of blood loss
Side effect
Time frame · During intra-opeartion and acute post operation period as 24 hours post operation
type of side effect
Hemoglobin level
Time frame · Pre-operation and 24 hours post operation
differentiation of hemoglobin
Eligibility
Who can take part.
- Minimum age
- 18 Years
- Maximum age
- Not reported
- Sex
- FEMALE
- Healthy volunteers
- Yes
Inclusion Criteria: * previous history of postpartum hemorrhage * polyhydramnios * fetal macrosomia * previous cesarean section * grand multiparity * intramural myoma * chorioamnionitis * prolonged premature rupture of membrane * augmentation of labour Exclusion Criteria: * pregnancy induce hypertension * on anticoagulant * placenta previa or placenta percreta
Study locations
1 registered sites.
Thailand. Showing up to 24 locations stored in the fast local snapshot.
Rajavithi Hospital
Bangkok, Thailand
Publications
Results and literature.
No PMID-linked publications were present in this registry snapshot.
Related trials
More studies on Carbetocin.
NCT IDStudyPhase / statusEnrollmentUpdated
The Efficacy of Carbitocin in Reduction of Blood Loss During Myomectomy
Alex Ekwueme Federal University Teaching Hospital · Blood Loss, Surgical
Early Phase 1
Not yet recruiting
900
2026-07
Carbetocin Monotherapy Versus Carbetocin Plus Oxytocin Infusion in Elective Cesarean Delivery: A Non-Inferiority Trial
Mansoura University · Postpartum Hemorrhage · Uterine Atony
Phase 4
Not yet recruiting
332
2026-06
Carbetocin Uterotonic Treatment in Twin Pregnancies for Prevention of Postpartum Hemorrhage
Sheba Medical Center · Postpartum Hemorrhage · Twin Pregnancy
Phase 4
Recruiting
120
2026-05
Comparing the Dose-response Profiles of Uterotonics After Initial Carbetocin Administration - an Ex-vivo Study in Desensitized Human Myometrium
Samuel Lunenfeld Research Institute, Mount Sinai Hospital · Postpartum Hemorrhage
Not applicable
Recruiting
32
2026-04
Comparative Efficacy of Carbetocin and Oxytocin in Parturients at Risk of Atonic Postpartum Hemorrhage Undergoing Elective Cesarean Delivery
Samuel Lunenfeld Research Institute, Mount Sinai Hospital · Post Partum Hemorrhage
Not applicable
Recruiting
160
2026-04
Effect of Co-administration of Carbetocin and Calcium Chloride on Uterine Tone in Patients Undergoing Elective Cesarean Delivery
Samuel Lunenfeld Research Institute, Mount Sinai Hospital · Postpartum Hemorrhage (Primary)
Not applicable
Recruiting
120
2026-04
Comparison of the Effect of Carbetocin Versus Oxytocin in the Prevention of Postpartum Hemorrhage After Emergency Caesarean Section in Antenatal Low-risk Patients
Ankara Etlik City Hospital · Postpartum Hemorrhage \(PPH\)
Not applicable
Completed
300
2026-02
Carbetocin Myocardium Trial 2014 Part 2
Oslo University Hospital · Pregnancy Complications
Phase 4
Completed
240
2026-02
Related PeptideStat pages
Put the record in context.
Research pages describe evidence. Vendor pages, where available, describe independently tracked research-product listings and are not clinical recommendations.