Development-stage index

Early Phase 1Peptide Trials.

Explore every Early Phase 1 peptide study in the local registry snapshot. Compare recruitment, sponsors, therapeutic areas, enrollment, results, publications and study geography.

Studies: 40
Recruiting: 9
Completed: 13
Results posted: 1
Countries: 9
Avg enrollment: 68

Velocity

Early Phase 1 trials by start year

Study start year · indexed snapshot

Development

Trials by phase

40phase labels

Early Phase 140

Phase 10

Phase 20

Phase 30

Phase 40

Industry

Leading sponsors

Therapeutic areas

Condition groups

Weight loss3

Longevity2

Brain health1

Pain1

Type 2 diabetes1

Compound leaders

Most represented peptides.

01Ganirelix6 02Degarelix4 03Cetrorelix3 04Oxytocin3 05Triptorelin3 06Vasopressin3 07Atosiban2 08Carbetocin2 09Exenatide2 10Pramlintide2 11Secretin2 12Calcitonin1

Study explorer

Search this collection.

40 matching studies

Last registry update first

NCT07732348Early Phase 1

Oral GnRH Antagonist (Linzagolix) Versus Injectable GnRH Antagonist for Ovarian Stimulation in IVF/ICSI

Cetrorelix GanirelixCentro A.M.B.R.A. (Associazione Medici e Biologi per la Riproduzione Assistita)Infertility, Female · Ovulation Induction

Not yet recruiting

Enrollment: 189
Started: Sep 2026
Completion: Dec 2026
Locations: 0
Countries: 0
Updated: Jul 2026

NCT07727473Early Phase 1

Preoperative Semaglutide Prior to Radical Prostatectomy

SemaglutideBanner HealthProstate Cancer

Not yet recruiting

Enrollment: 20
Started: Jul 2026
Completion: May 2029
Locations: 1
Countries: 1
Updated: Jul 2026

NCT07568509Early Phase 1

Identifying Oxytocin Deficiency in Pediatric Patients With Pituitary Disease

Vasopressin OxytocinMassachusetts General HospitalArginine Vasopressin Deficiency · Oxytocin Deficiency

Recruiting

Enrollment: 20
Started: Aug 2026
Completion: Apr 2027
Locations: 1
Countries: 1
Updated: Jul 2026

NCT07721623Early Phase 1

The Efficacy of Carbitocin in Reduction of Blood Loss During Myomectomy

CarbetocinAlex Ekwueme Federal University Teaching HospitalBlood Loss, Surgical

Not yet recruiting

Enrollment: 900
Started: Aug 2026
Completion: Aug 2028
Locations: 0
Countries: 0
Updated: Jul 2026

NCT06934642Early Phase 1

Effect of Tirzepatide on Markers of MASLD in Patients With Obesity

Tirzepatide GlucagonUniversity of New MexicoMASLD · Obesity

Recruiting

Enrollment: 8
Started: Jun 2025
Completion: Aug 2026
Locations: 1
Countries: 1
Updated: Jul 2026

NCT03560960Early Phase 1

Multi-Center Development of a Novel Diagnostic Test for Alzheimer's Disease

PramlintideBoston UniversityAlzheimer Disease · Mild Cognitive Impairment

Active, not recruiting

Enrollment: 57
Started: Feb 2020
Completion: Nov 2026
Locations: 3
Countries: 1
Updated: May 2026

NCT06460948Early Phase 1

Identifying Oxytocin Deficiency in Adults With Pituitary Disease

Vasopressin OxytocinElizabeth Austen LawsonArginine Vasopressin Deficiency · Oxytocin Deficiency

Completed

Enrollment: 28
Started: Nov 2024
Completion: Mar 2026
Locations: 1
Countries: 1
Updated: May 2026

NCT07569419Early Phase 1PubMed

Proof of Principle Study for an Efficacy Trial of Linaclotide for Cystic Fibrosis

LinaclotideUniversity of NottinghamCystic Fibrosis (CF)

Recruiting

Enrollment: 26
Started: Mar 2026
Completion: Oct 2026
Locations: 1
Countries: 1
Updated: May 2026

NCT07568275Early Phase 1

Comparison of Angiotensin II to Standard Dose Vasopressors on Change in Arterial Elastance

VasopressinThe Cleveland ClinicSeptic Shock · Cirrhosis

Active, not recruiting

Enrollment: 30
Started: Nov 2024
Completion: Jan 2028
Locations: 1
Countries: 1
Updated: May 2026

NCT05761860Early Phase 1

The Potential of Oxytocin to Reduce Opioid Abuse Liability and Pain Among Older Adults

OxytocinUniversity of FloridaPain

Recruiting

Enrollment: 45
Started: Sep 2023
Completion: Jul 2027
Locations: 1
Countries: 1
Updated: May 2026

NCT06803589Early Phase 1

Growth Hormone for the Treatment of Gastroparesis

SomapacitanMayo ClinicGastroparesis

Recruiting

Enrollment: 10
Started: Oct 2024
Completion: Dec 2027
Locations: 2
Countries: 1
Updated: Apr 2026

NCT07516704Early Phase 1

Safety and Efficacy of Docetaxel, Darolutamide, and Homoharringtonine Combined With Androgen Deprivation Therapy in Neoadjuvant Treatment of High-Risk Prostate Cancer: A Multicenter Prospective, Single-Arm Clinical Study

GoserelinZhongda HospitalProstate Cancer

Not yet recruiting

Enrollment: 94
Started: Apr 2026
Completion: Dec 2027
Locations: 0
Countries: 0
Updated: Apr 2026

NCT07347080Early Phase 1

A Single-Center, Open-Label, Single Ascending Dose Study of Exenatide Circular RNA-Lipid Nanoparticle Injection (CR059) in Chinese Subjects With Type 2 Diabetes Mellitus

ExenatideThe First Affiliated Hospital of Henan University of Science and TechnologyT2DM

Recruiting

Enrollment: 9
Started: Jan 2026
Completion: Aug 2026
Locations: 1
Countries: 1
Updated: Apr 2026

NCT06171152Early Phase 1

Study of Liraglutide (A Weight Loss Drug) in High Risk Obese Participants With Cognitive and Memory Issues

LiraglutideUniversity of ChicagoMultiple Sclerosis · Long COVID

Suspended

Enrollment: 30
Started: Jan 2024
Completion: Oct 2027
Locations: 1
Countries: 1
Updated: Mar 2026

NCT07389174Early Phase 1

Safety and Efficacy Evaluation of LC-K76 in Patients With Metastatic Hormone-Sensitive Prostate Cancer

Degarelix TriptorelinShanghai Changzheng HospitalmHSPC · mHNPC

Not yet recruiting

Enrollment: 40
Started: Feb 2026
Completion: Jun 2027
Locations: 1
Countries: 1
Updated: Feb 2026

NCT07389187Early Phase 1

Safety and Preliminary Efficacy Evaluation of LC-K76 Plus Anti-PD-1 Therapy in Patients With Metastatic Castration-Resistant Prostate Cancer (mCRPC)

Degarelix TriptorelinShanghai Changzheng HospitalmCRPC

Not yet recruiting

Enrollment: 10
Started: Feb 2026
Completion: Jun 2028
Locations: 1
Countries: 1
Updated: Feb 2026

NCT03511196Early Phase 1PubMed

Intermittent Androgen Deprivation Therapy for Stage IV Castration Sensitive Prostate Cancer

TriptorelinH. Lee Moffitt Cancer Center and Research InstituteProstate Cancer · Stage IV Prostate Cancer

Active, not recruiting

Enrollment: 17
Started: Sep 2018
Completion: Sep 2026
Locations: 1
Countries: 1
Updated: Dec 2025

NCT04037605Early Phase 1

Hormonal Mechanisms of Sleep Restriction - Axis Study in Older Men and Postmenopausal Women

GanirelixLundquist Institute for Biomedical Innovation at Harbor-UCLA Medical CenterSleep Restriction

Active, not recruiting

Enrollment: 5
Started: Feb 2020
Completion: Jun 2026
Locations: 1
Countries: 1
Updated: Sep 2025

NCT02823665Early Phase 1

The Effects of Bariatric Surgeries on Glucose Metabolism

SecretinThe University of Texas Health Science Center at San AntonioPost Bariatric Surgery · Gastric Bypass

Recruiting

Enrollment: 200
Started: Jul 2015
Completion: Aug 2027
Locations: 2
Countries: 1
Updated: Sep 2025

NCT07140237Early Phase 1

The Effect of Oral Oxytocin and Atosiban on Top-down Attention ( OTAtosiban )

AtosibanUniversity of Electronic Science and Technology of ChinaHealthy Adult Male

Recruiting

Enrollment: 250
Started: Sep 2025
Completion: Dec 2025
Locations: 1
Countries: 1
Updated: Sep 2025

NCT04301414Early Phase 1PubMed

Non-fucosylated Anti-CTLA-4 (BMS-986218) + Degarelix Acetate vs. Degarelix Acetate Alone in Men With High-risk Localized Prostate Cancer

DegarelixColumbia UniversityProstate Cancer

Completed

Enrollment: 26
Started: Feb 2020
Completion: Mar 2025
Locations: 1
Countries: 1
Updated: Aug 2025

NCT07093060Early Phase 1

The Effect of Oral Oxytocin and Atosiban on Social Attention

AtosibanUniversity of Electronic Science and Technology of ChinaHealhty

Recruiting

Enrollment: 250
Started: Jun 2025
Completion: Nov 2025
Locations: 1
Countries: 1
Updated: Jul 2025

NCT05751252Early Phase 1

Sub-therapeutic GnRH- Antagonist Treatment to Rectify LH Pulsatility in Lean Women With PCOS.

GanirelixUniversity Hospital, LillePolycystic Ovary Syndrome

Completed

Enrollment: 20
Started: Apr 2024
Completion: Feb 2025
Locations: 1
Countries: 1
Updated: Apr 2025

NCT06778733Early Phase 1PubMed

Effectiveness of Low Dose Gonadotropin Stimulation Protocol Vs High Dose Gonadotropin Protocol in Poor Responders

CetrorelixUniversity of AthensFemale Infertility

Completed

Enrollment: 22
Started: Jan 2022
Completion: Apr 2024
Locations: 2
Countries: 1
Updated: Jan 2025