Novel Breath Test to Detect Early Stage Chronic Pancreatitis

Inclusion Criteria: * Male of female greater than or equal to 18 years of age. * Subjects must have the ability to give informed consent. * Female subjects of child bearing potential must use a medically acceptable form of birth control and have a negative pregnancy test. * For case subjects with mild to moderate chronic pancreatitis, they must have either an abnormal endoscopic ultrasound (greater than 4 abnormalities), an abnormal secretin stimulation test, an abnormal endoscopic retrograde cholangiopancreatography (ERCP), an abnormal CT scan of the pancreas (dilation of the main pancreatic duct or atrophy of the pancreas), a serum trypsin level \<29 ng/ml but \>20 ng/ml, or a fecal elastase of less than 200 mcg/gram stool but greater than 100 mcg/gram stool. Exclusion Criteria: * Females who are lactating or pregnant. * Subjects with acute pancreatitis. * Subjects known to have a significant medical and/or mental disease. * Subjects receiving an investigational new drug within 30 days. * Subjects on enzyme therapy, proton pump inhibitors, H2 receptor antagonists. * Subjects who have had a recent febrile illness within 5 days of scheduled entry into the study. Body temperature must be normal for at least 72 hours before entering the study.